General Information

  • ID:  hor004305
  • Uniprot ID:  A0A8J5MMN2
  • Protein name:  Tachykinin
  • Gene name:  NA
  • Organism:  Homarus americanus (American lobster)
  • Family:  Tachykinin family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Homarus (genus), Nephropidae (family), Nephropoidea (superfamily), Astacidea (infraorder), Pleocyemata (suborder), Decapoda (order), Eucarida (superorder), Eumalacostraca (subclass), Malacostraca (class), Multicrustacea (superclass), Crustacea (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  APSGFLGMR
  • Length:  9
  • Propeptide:  MVRACTWAVLLGVVVVMGVVSAAGEGQDTPQDRERRAPSGFLGMRGKKDASTALDDNTAASEYSSLPDPYPLYGLRDNNLPMLFAVPWKTKKAPSGFLGMRGKKSDEEVFSDATADNDLEILLKRAPSGFLGMRGKKAPSGFLGMRGKKAPSGFLGMRGKKYYDDDSDMDAYIQALTAVVDGQQQQKRAPSGFLGMRGKKAYYSENPDEEISMTGVDKRTPSGFLGVRCSLHSALPCLKIIPRAVIPA
  • Signal peptide:  MVRACTWAVLLGVVVVMGVVSA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor004305_AF2.pdbhor004305_ESM.pdb

Physical Information

Mass: 107798 Formula: C41H66N12O11S
Absent amino acids: CDEHIKNQTVWY Common amino acids: G
pI: 10.55 Basic residues: 1
Polar residues: 3 Hydrophobic residues: 3
Hydrophobicity: 28.89 Boman Index: -438
Half-Life: 4.4 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 54.44
Instability Index: 4331.11 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  22860213
  • Title:  Mass Spectral Charting of Neuropeptidomic Expression in the Stomatogastric Ganglion at Multiple Developmental Stages of the Lobster Homarus Americanus